下垂体脑梗塞的自然史:长期随访研究
Ayesha A Shaikh1, David Michael Williams1, Jeffrey Wayne Stephens1
1Endocrine and Diabetes, Morriston Hospital, Swansea, UK.
Postgraduate medical journal
|June 15, 2023
概括
下垂体脑梗塞 (PA) 经常发生在未被诊断的腺瘤中. 虽然外部眼膜已经消失,但视力损失仍然存在,脑下垂体瘤复发很少.
科学领域:
- 神经外科 神经外科
- 内分泌学 在内分泌学.
- 眼科医生 眼科 眼科
背景情况:
- 垂体脑梗塞 (PA) 是一种罕见的神经外科紧急情况.
- 胰腺动症与垂体激素缺乏有关.
- 对于PA的保守性与外科手术干预结果存在有限的研究.
研究的目的:
- 为了评估对 pituitary apoplexy 的保守和神经外科干预的结果.
- 分析患者的特征和PA的表现.
- 评估长期的后果和复发率.
主要方法:
- 在莫里斯顿医院 (1998-2019) 的PA患者的回顾性审查.
- 通过医院数据库,诊所信件和出院摘要确认了诊断.
- 分析治疗方法 (保守,手术,放射治疗) 和患者的治疗结果.
主要成果:
- 确定了39名PA患者 (平均年龄为74.5岁,51.3%为女性).
- 59%的人有已知的垂体腺瘤;87.2%的人呈现出非功能性腺瘤.
- 外部眼在所有病例中都消失;视力损失持续. 复发和进一步的PA发作是罕见的.
结论:
- 在未被诊断的垂体腺瘤患者中,PA经常发生.
- 在保守和外科手术治疗后,低垂体是常见的.
- 虽然眼通常会消失,但视力缺陷可能是永久的;PA复发很少发生.
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