机构通风COVID-19病例数量与医院死亡之间的关系:一个多中心队列研究
Shunsuke Amagasa1, Satoko Uematsu2, Mitsuru Kubota2
1Division of Emergency and Transport Services, National center for Child Health and Development, Okura, Setagaya-ku, Tokyo, Japan.
PloS one
|June 15, 2023
概括
这项研究发现,在需要通风的严重COVID-19患者中,医院病例数量和死亡率之间没有显著的联系. 较高体积的中心对通风的2019年冠状病毒病患者没有显示出更好的结果.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 医院病例数量与严重的冠状病毒疾病2019 (COVID-19) 患者结果之间的关系尚不清楚.
- 了解这种体积-结果关系对于为严重的COVID-19患者开发有效的医疗保健系统至关重要.
研究的目的:
- 调查机构病例数量与需要机械通风的严重COVID-19病例患者结果之间的关联.
- 为了确定更高体积的中心是否会导致严重病情的COVID-19患者的生存率提高.
主要方法:
- 来自J-RECOVER研究 (2020年1月至9月,日本) 的561名需要机械通风的严重COVID-19患者的回顾性分析.
- 根据通风COVID-19患者的体积,机构被分为低体积 (<11例),中体积 (11-25例) 和高体积 (>25例) 的机构.
- 多变量逻辑回归被用来分析住院死亡率,调整为倾向得分和住院变量.
主要成果:
- 分析包括36个低体积,14个中体积和5个高体积机构的561名患者.
- 在调整后,在中量 (aOR 0.77,95% CI 0.46-1.29) 或高量 (aOR 0.76,95% CI 0.44-1.33) 的中心与低量中心相比,在住院死亡率中没有显著差异.
- 这些发现表明,机构病例数量可能不会显著影响COVID-19患者的死亡率.
结论:
- 这项研究表明,对于患有严重的,通风性COVID-19的患者,机构病例数量和住院死亡率之间可能缺乏显著的关联.
- 可能需要进一步的研究来证实这些发现,并探索其他影响严重COVID-19护理结果的因素.
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