T-BACCO SCORE:结核病 (结核病) 损失的预测评分工具,用于结核病吸烟者的随访
Zatil Zahidah Sharani1, Nurhuda Ismail1,2, Siti Munira Yasin1,2
1Department of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia.
PloS one
|June 15, 2023
概括
一个新的T-BACCO SCORE工具可以预测吸烟的结核病患者的随访损失 (LTFU). 这一分数有助于管理结核病吸烟者,改善治疗结果,减少结核病控制计划的挑战.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 临床医学 临床医学
背景情况:
- 失去跟踪 (LTFU) 和吸烟是结核病 (TB) 控制的重大障碍.
- 吸烟加剧了结核病的严重程度,并延长了治疗时间,增加了LTFU的发病率.
研究的目的:
- 开发一种预后评分工具,以预测吸烟的结核病患者中的LTFU.
- 帮助结核病控制计划改善吸烟者的治疗结果.
主要方法:
- 利用马来西亚结核病信息系统 (MyTB) 中的吸烟成人结核病患者 (2013-2017) 的纵向数据.
- 使用后勤模型开发了T-BACCO SCORE,并在内部验证了它.
- 使用c统计 (AUC) 评估模型歧视,并使用Hosmer和Lemeshow测试进行校准.
主要成果:
- "T-BACCO SCORE"包括年龄,种族,收入,就业和结核病状况等变量.
- 评分分为低 (<15),中等 (15-25) 和高 (>25) 的LTFU风险.
- 该模型显示了公平的歧视 (c-statistic=0.681) 和良好的校准 (p=0.769).
结论:
- T-BACCO SCORE有效地预测了结核病患者在治疗早期吸烟的LTFU.
- 该工具可以帮助医疗保健专业人员根据风险分层管理结核病吸烟者.
- 在广泛临床实施之前,建议进行外部验证.
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