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对于囊性纤维化而言,雾化高性盐水可用于囊性纤维化
Peter Wark1, Vanessa M McDonald2, Sherie Smith3
1Centre for Healthy Lungs, Hunter Medical Research Institute, University of Newcastle, New Lambton, Australia.
The Cochrane database of systematic reviews
|June 15, 2023
概括
在患有囊性纤维化 (CF) 的幼儿中,雾化过敏盐水可以改善肺清除指数. 对于成人和老年儿童的证据是不确定的,重组脱氧核糖核酶 (rhDNase) 可能会提供更好的肺功能改善.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 肺部病理学 肺部病理学
- 临床试验 临床试验
背景情况:
- 高血压盐水 (HS) 正在研究其增强粘膜细胞清除和减少囊性纤维化 (CF) 中的呼吸道炎症的潜力.
- 本综述是更新,重点关注CF患者中雾化HS的疗效和耐受性.
结论:
- 在急性CF肺部恶化期间,雾化HS可能是物理治疗的有效补充.
- 与CF中HS相关的大多数结局的证据确定性非常低至低.
- 未来的研究应该与CFTR调节器疗法一起探索HS的作用.
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