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对皮质类固醇的接触过敏:欧洲基线系列是否足够?
Sebastian Vigand Svendsen1, Carsten Bindslev-Jensen1, Charlotte G Mortz1
1Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense C, Denmark.
Contact dermatitis
|June 15, 2023
概括
对皮质类固醇的接触过敏可以在TRUE测试中有效地使用布德索尼德,蒂克索科托尔-21-皮瓦拉酸盐和皮质-17-酸盐进行查. 补充贴片测试对于识别共同敏感化模式至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 过敏学 过敏学
- 接触性皮肤炎是一种皮肤炎.
背景情况:
- 在皮质类固醇接触过敏查中,在欧洲基线系列中使用了布德索尼德和蒂克索科托-21-皮瓦拉酸.
- TRUE测试包括皮-17-酸盐,并为疑似病例提供补充系列.
研究的目的:
- 在TRUE测试中评估皮质类固醇的疗效.
- 研究皮质类固醇过敏患者的共同敏感化模式.
主要方法:
- 在2006-2020年间对1852名患者进行了补丁测试的回顾性分析.
- 使用 TRUE 测试皮质类固醇与补充皮质类固醇系列一起使用.
- 数据来自奥登塞大学医院皮肤病学系和过敏中心.
主要成果:
- 在1852名患者中,有119名患者对TRUE测试皮质类固醇表现出敏感性.
- 补充测试发现了19名患者的额外皮质类固醇反应.
- 14%的敏感患者表现出对多个皮质类固醇组的共同敏感性;贝克组3的皮质类固醇发现了16例遗漏病例中的9例.
结论:
- 布德索尼德,皮-17-丁酸盐和皮-21-皮瓦酸盐作为皮质类固醇过敏的敏感标志物.
- 强烈建议在临床上怀疑皮质类固醇接触过敏时进行补充皮质类固醇贴片测试.
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