对治疗偏头痛和预防偏头痛的共识建议
Miguel Ángel Calleja-Hernández1, Ángel Luis Guerrero-Peral2, Pablo Irimia-Sieira3
1Servicio de Farmacia Hospitalaria, Hospital Virgen Macarena, Sevilla, España.
概括
神经学家和药剂师在很大程度上同意抗CGRP单克隆抗体用于偏头痛预防,确定改善患者护理和治疗准入的关键领域.
科学领域:
- 神经学 神经学
- 药理学 药理学是指药理学的学科.
- 医疗保健管理的管理
背景情况:
- 偏头痛预防仍然是一个挑战,围绕新型治疗方法的持续辩论.
- 反CGRP单克隆抗体代表了偏头痛预防的重大进展.
研究的目的:
- 确定神经科医生和医院药剂师关于预防偏头痛的抗CGRP单克隆抗体的意见.
- 识别和解决这些生物药物的使用中存在的争议.
- 制定基于共识的建议,以优化患者护理和治疗机会.
主要方法:
- 德尔菲共识方法用于评估生物偏头痛预防建议.
- 在临床,患者和协调模块中开发了88个陈述.
- 数据分析使用9点利克特比例和统计指标.
主要成果:
- 在88个陈述中有71个 (80.7%) 达成共识.
- 高达成一致表明,关于抗CGRP单克隆抗体的类似专家意见.
- 确定了争议和改善临床实践的领域.
结论:
- 神经学家和药剂师之间对于抗CGRP单克隆抗体的作用有强烈的共识.
- 调查结果有助于识别现有争议.
- 这些建议旨在加强对患者的护理和偏头痛管理中的随访.
相关概念视频
Venous Thrombosis III: Interprofessional Care
11
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
11
Management of Insomnia
284
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
284
Open Angle Glaucoma: Treatment
491
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
491
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
252
5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
252
Cholinergic Antagonists: Therapeutic Uses
784
Antimuscarinic drugs have various therapeutic applications by inhibiting parasympathetic stimulation in different systems. Here are the key therapeutic uses of antimuscarinics:
Respiratory Tract: Ipratropium, aclidinium, and tiotropium treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). They protect against bronchoconstriction caused by irritants like cigarette smoke, sulfur dioxide, and ozone. They also help reduce nasopharyngeal...
Respiratory Tract: Ipratropium, aclidinium, and tiotropium treat asthma, chronic bronchitis, and chronic obstructive pulmonary disease (COPD). They protect against bronchoconstriction caused by irritants like cigarette smoke, sulfur dioxide, and ozone. They also help reduce nasopharyngeal...
784
Antidepressant Drugs: MAOIs and Other Agents
280
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
280


