围产期精神药物开放:一种基于新西兰人口的描述性研究
Lucy Charlotte Broughton1, Natalie Hughes-Medlicott1, Jiaxu Zeng2
1School of Pharmacy, University of Otago, Dunedin, New Zealand.
概括
在新西兰,约有6.6%的怀孕涉及向心理药物开放. 许多服用抗抑郁药或抗精神病药的妇女在怀孕期间停止服用这些药物,影响母亲的心理健康决策.
科学领域:
- 围产期心理健康问题
- 生殖精神病学是一种精神病学.
- 公共卫生监督是对公共卫生的监督.
背景情况:
- 平衡未经治疗的母亲疾病风险与胎儿暴露于精神药物中的风险是一个复杂的临床挑战.
- 了解怀孕期间的精神药物开放模式对于明智的临床决策和公共卫生政策至关重要.
- 这项研究解决了描述新西兰当前围产期精神药物开放趋势的需要.
研究的目的:
- 在新西兰,描述整个怀孕期间的精神药物分发模式.
- 为了确定在不同药物类别和怀孕期间使用精神药物的流行程度.
- 分析在怀孕前使用心理药物的女性中,包括停药在内的开药模式.
主要方法:
- 利用来自新西兰国家孕产妇数据 (2011-2017年) 的全国数据.
- 将399,715例怀孕的产妇记录与分发数据联系起来.
- 根据精神药物类别,年份,怀孕期和母亲的特征计算了发药比例;分析了怀孕前发药的妇女的停药模式.
主要成果:
- 6.6%的怀孕至少有一次使用精神药物.
- 抗抑郁药最常见 (5.1%),其次是催眠药 (1.2%),抗焦虑药 (0.7%) 和抗精神病药 (0.7%).
- 在怀孕前处方的女性中,观察到催眠药 (91%),抗焦虑药 (90%), (71%),抗精神病药 (66%) 和抗抑郁药 (66%) 的高停药率.
结论:
- 在约6.6%的新西兰怀孕中,精神药物被处方.
- 很大一部分女性,特别是那些服用抗抑郁药或抗精神病药的人,在怀孕期间停止服用这些药物 (66%).
- 这些发现强调需要进一步调查关于在怀孕期间使用精神药物的决策过程,以支持母亲的心理健康.
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