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从几何学规定的心内流量计算流体动力学:与超声波矢量流量成像进行比较

Rasmus Hvid¹, Matthias Bo Stuart¹, Jørgen Arendt Jensen¹

¹Department of Health Technology, Technical University of Denmark, 2800, Kongens Lyngby, Denmark.

Cardiovascular engineering and technology

|June 15, 2023

概括

这项研究验证了计算流体动力学 (CFD) 模拟与超声波向量流成像 (VFI) 在动态心脏幻影中. CFD准确地预测了入口/出口附近的血液流速,支持其在心血管研究中的使用.

科学领域:

生物医学工程生物医学工程
医疗成像医学成像
流体动力学流体动力学

背景情况:

计算流体动力学 (CFD) 越来越多地用于模拟血液流动.
对实验数据的验证对于CFD准确性至关重要.
动态心脏幻影为测试心血管模型提供了一个受控的环境.

研究的目的:

为了评估模拟血流速度的几何规定的CFD管道的准确性.
将CFD模拟的流量模式与超声波矢量流量成像 (VFI) 的直接测量进行比较.
为了确定模拟的速度大小是否在测量速度的标准偏差范围内.

主要方法:

使用计算机断层扫描血管学 (CTA) 图像用于CFD几何输入.
使用体积图像注册来规定流体域运动.
在平行平面上测量VFI并与模拟的3D流体速度场进行比较.

主要成果:

定性比较显示VFI和CFD之间的流动模式类似.
定量分析显示,模拟和测量速度之间的强相关性 (R2=0.823) 在异常排除后.
在CFD和VFI之间的标准偏差为0.048 m/s.

结论:

差价合约管道在动态的心脏幻影中产生现实的流动模式.
获得的精度在入口和出口区域附近很高.
对于远离入口/出口的地区,可能需要进一步精细化.

关键词:

计算流体动力学计算流体动力学几何学规定了运动的运动.内心心脏血液动力学超声波血液流动成像超声波血液流动成像

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