在患有异形性和JIA相关性脑膜炎的儿童中,鼓励视觉结果:基于人口的研究
Mira Siiskonen1,2,3, Iida Hirn2,3, Roosa Pesälä2,3
1Department of Ophthalmology, Oulu University Hospital, Oulu, Finland.
Pediatric rheumatology online journal
|June 15, 2023
概括
儿科紫外线炎,通常与青少年异常性关节炎有关,通常导致视力良好,视力受损率低. 像DMARDs和bDMARDs这样的现代治疗方法似乎可以有效地保护儿童的视力.
科学领域:
- 眼科医生 眼科 眼科
- 儿科风湿病学 儿科风湿病学
- 临床研究 临床研究
背景情况:
- 儿科卵膜炎可以无症状和慢性,影响眼部结构和视力.
- 这项研究将异常性脑膜炎 (idio-U) 与儿童性异常性关节炎相关性脑膜炎 (JIA-U) 进行比较.
- 评估的关键参数包括视觉结果,临床特征,药物和脑膜炎活动.
研究的目的:
- 评估和比较视觉结果,临床特征,治疗方法和疾病活性.
- 评估儿科患者上皮炎的长期影响.
- 确定当前治疗方法在治疗儿科紫外线炎的疗效.
主要方法:
- 一项从2008年至2017年进行的基于人口的纵向队列研究.
- 包括119名16岁以下的儿童被诊断患有耳膜炎.
- 收集的数据包括人口统计,脑膜炎的特征,治疗方法 (皮质类固醇,DMARD,bDMARD) 和视力敏度.
主要成果:
- 青春期异常性关节炎相关性脑膜炎 (JIA-U) 的发病率比异常性脑膜炎 (idio-U) (23%) 的发病率高 (77%).
- JIA-U患者更常见的是女性,并且在较年轻时被诊断出来 (5.5岁与10.0岁相比).
- 大多数患者保持正常的视力敏度;只有4%的患者在一只眼睛出现视力损伤,双眼没有. 在JIA-U中,DMARD和bDMARD的使用率更高.
结论:
- 儿科内膜炎,包括JIA-U,与良好的视觉结果和较低的视力损伤发病率有关.
- 使用疾病修饰性抗风湿药物 (DMARDs) 和生物DMARDs (bDMARDs) 与子宫膜炎儿童的视力保持有关.
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