胃肠道出血在连续流动的左心室辅助装置治疗治疗上的胃肠道出血
Yoav Hammer1, Abbas Bitar1, Keith D Aaronson1
1Division of Cardiovascular Disease, Michigan Medicine - University of Michigan, Ann Arbor, MI, USA.
ESC heart failure
|June 16, 2023
概括
持续流动左心室辅助装置 (CF-LVAD) 接受者经常出现胃肠道出血 (GIB),这是一个常见且严重的不良事件. 本综述研究了CF-LVAD患者的GIB原因,风险和治疗方法.
科学领域:
- 心血管外科心血管外科
- 医疗器械技术 医疗器械技术
- 胃肠病学 胃肠病学
背景情况:
- 持续流动的左心室辅助器件 (CF-LVADs) 对于高级心力衰竭管理至关重要.
- 尽管技术进步,CF-LVAD接受者面临重大不良事件,最常见的是胃肠道出血 (GIB).
- 后LVAD GIB严重影响生活质量,需要住院治疗,输血,并可能导致死亡.
研究的目的:
- 审查LVAD后GIB的病因,发病率和风险因素.
- 评估CF-LVAD接受者对GIB的当前和新兴治疗选择.
- 讨论下一代CF-LVADs对GIB发生和管理的影响.
主要方法:
- 这是一篇综述性文章,综合了关于LVAD后GIB的现有文献.
- 从注册表数据和已发表的研究中收集信息.
- 重点是确定风险因素,治疗疗效和与设备相关的影响.
主要成果:
- 胃肠道出血是CF-LVAD接受者中最常见的不良事件.
- 复发性GIB是常见的,加剧了患者的发病率.
- 目前医疗和内镜治疗的证据在很大程度上是模两可的,临床试验数据有限.
结论:
- 缺乏有效的植入前查工具来预测GIB.
- 需要进一步的研究,包括临床试验,以建立最佳的GIB管理策略.
- 了解和减轻GIB风险对于改善CF-LVAD患者的治疗结果至关重要.
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