机械血栓切除术用于脑静脉血栓形成的利用趋势和结果:国家住院样本研究
Waseem Wahood1, Ahraz Ahsan Rizvi1, Vikram Patel1
1Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Davie, FL, USA.
概括
对脑静脉血栓 (CVT) 的机械血栓切除 (MT) 越来越多地使用. 虽然MT利用率正在上升,但非家庭出院 (DOTH) 率保持稳定,昏迷或脑患者的死亡率更高.
科学领域:
- 神经学 神经学
- 干预神经病学 干预神经病学
- 血管神经学 血管神经学
背景情况:
- 大脑静脉血栓症 (CVT) 管理通常涉及全身抗凝药.
- 机械血栓切除术 (MT) 和局部血栓溶解正在成为CVT替代疗法.
- 本研究分析了MT利用,排放处置和CVT死亡率的趋势.
研究的目的:
- 确定机械血栓切除术 (MT) 在脑静脉血栓症 (CVT) 病例中的使用趋势.
- 分析接受MT进行CVT的患者在非家庭出院 (DOTH) 的趋势.
- 评估与CVT的MT相关的住院死亡率.
主要方法:
- 从2005年到2018年对CVT和MT病例的国家住院样本 (NIS) 数据库的分析.
- 考克兰-阿米塔奇测试用于评估MT利用和DOTH的线性趋势.
- 多变量后勤回归用于识别与MT使用,死亡率和DOTH相关的因素.
主要成果:
- 在85,370名CVT招生中,MT被用于1.56%,显示每年利用率增加0.13%.
- 在MT招生中,DOTH的比例保持稳定 (趋势为0.70%).
- 大脑和血液学障碍增加了MT的几率;昏迷和大脑增加了死亡率.
结论:
- 机械血栓切除术 (MT) 对脑静脉血栓症 (CVT) 的利用正在增加.
- 在MT之后,非家庭 (DOTH) 排放处置率对CVT保持稳定.
- 脑和昏迷等更高的风险因素与MT使用和死亡率的增加有关.
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