无机声敏剂用于癌症治疗中的声动疗法
Xianshuo Cao1, Minxing Li1,2, Qiyu Liu1
1Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, School of Chemistry, Sun Yat-sen University, Guangzhou, 510275, P. R. China.
Small (Weinheim an der Bergstrasse, Germany)
|June 16, 2023
概括
无机声敏剂为声动疗 (SDT) 提供了增强的稳定性和多功能性. 本综述强调了他们对有效的非侵入性癌症治疗的进展和优化策略.
科学领域:
- 纳米医学和纳米生物技术
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
背景情况:
- 超声波疗法 (SDT) 是一种有前途的非侵入性癌症治疗方法,它结合了超声波和超声波敏感剂.
- 声敏剂对于SDT的有效性至关重要,无机材料比有机材料具有优势.
- 无机声敏剂表现出优越的稳定性,形态控制和多功能性,以提高治疗效果.
研究的目的:
- 审查最近在 SDT 的无机声敏化剂方面的进展.
- 总结无机声敏剂的配方,抗瘤效果和优化策略.
- 讨论开发用于癌症治疗的无机声敏剂的挑战和未来前景.
主要方法:
- 对SDT中无机声敏剂的最新文献进行系统审查.
- 讨论SDT机制,包括腔化和反应性氧物种的产生.
- 对各种无机声敏剂类型 (贵金属,过渡金属,碳,基于) 的分析.
主要成果:
- 无机声敏剂由于其固有的特性,在SDT中显示出显著的潜力.
- 已经制定了各种无机材料,并对抗瘤作用进行了测试.
- 概述了利用无机声敏剂在SDT中优化治疗效率的策略.
结论:
- 无机声敏剂是一个快速发展的领域,有望通过SDT进行非侵入性癌症治疗.
- 对优化无机声敏剂的进一步研究对于临床转化至关重要.
- 本综述为未来开发和选有效无机声敏剂的SDT提供了见解.
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