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在早产婴儿的腹腔内出血的复杂性导航:一个更新的审查
Pulliahgaru Apeksha Reddy1, Himabindu Sreenivasulu2, Mohammad Shokrolahi3
1Pediatric Medicine, P.E.S. Institute of Medical Sciences and Research, Kuppam, IND.
Cureus
|June 16, 2023
概括
腹腔内出血 (IVH) 每年影响12000名美国早产婴儿. 本研究总结了早产新生儿的IVH病变发生,诊断和治疗,重点关注风险因素和管理.
科学领域:
- 新生儿医学 新生儿医学
- 儿科神经学 儿科神经学
- 医学遗传学 医学遗传学
背景情况:
- 腹腔内出血 (IVH) 是由于发育不良的生殖基质血管系统而导致过早产生的婴儿的关键病症.
- 在美国,每年大约有12,000名早产婴儿被诊断患有IVH,这在新生儿重症监护病房带来了重大风险.
- 虽然I级和II级IVH是常见的,通常无症状,但它们与特定的遗传突变有关.
研究的目的:
- 提供关于早产婴儿内腔室出血的发病,诊断和治疗的全面概述.
- 突出与新生儿IVH相关的风险因素和遗传倾向.
- 讨论目前IVH的诊断方式和支持性管理策略.
主要方法:
- 文献综述总结了有关IVH病变发生,发病率和风险因素的当前数据.
- 讨论诊断工具,包括头骨超声波和磁共振成像.
- 对早产婴儿IVH管理的既定治疗方案的概述.
主要成果:
- 过早出生的婴儿由于生殖基质不成熟,对IVH非常敏感.
- 遗传因素,如COL4A1,前列血G20210A和因子V莱登突变与I级和II级IVH相关.
- 通过神经成像在出生后7-14天内进行早期检测至关重要.
结论:
- 腹腔内出血是早产婴儿的一个重大问题,需要警的监测和管理.
- 支持性护理,包括内压力管理,凝血校正和预防,是IVH治疗的基石.
- 对病原和遗传联系的持续研究可以改善受影响新生儿的结果.
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