由于氨基粉症而引起的多流的特征
Cristina Pou1, Lucía Ferreiro2,3, Juan Suárez-Antelo2
1Department of Pulmonology, Álvaro Cunqueiro University Teaching Hospital, Vigo, Spain.
Annals of thoracic medicine
|June 16, 2023
概括
Amyloidosis (PA) 主要影响50岁以上的成年人,经常出现呼吸障碍和双边出血. 抗胰腺炎的治疗方法很少有效,这凸显了对更好的治疗选择的需求.
科学领域:
- 肺部病理学 肺部病理学
- 内部医学 内部医学
- 病理学 病理学 病理学
背景情况:
- Amyloidosis (PA) 是一种罕见的疾病,患者的特征不明.
- 现有的文献缺乏关于临床表现,肺部液体分析和治疗疗效的全面数据.
研究的目的:
- 系统地审查和综合有关 Amyloidosis 患者特征的现有数据.
- 确定常见的临床发现,多液 (PF) 概况和有效的治疗策略.
主要方法:
- 对病例描述和回顾性研究进行系统的审查,报告 Amyloidosis.
- 包括95项研究,包括196名患者.
- 分析患者的人口统计,症状,肺液特征,肺活检的诊断产量和治疗结果.
主要成果:
- 该研究主要在50岁以上的成年人中发现了PA (91.9%),平均年龄为63岁,男性占主导地位 (1.6:1).
- 呼吸障碍是最常见的症状 (88名患者). 胸腔液通常是双边的 (55%),血清性和淋巴细胞性,通常具有模两可的透/排特征.
- 胸腔活检在83.6%的病例中显示出诊断收益率. 治疗疗效总体较低 (12.4%),在一个小群体中,内置性肺膜导管的疗效更高 (75%).
结论:
- 腹粉样性粉症在老年人中更为普遍,并以特定的腹液发现为特征.
- 胸腔活检是一种有价值的诊断工具,特别是在单边或排泄性排泄时.
- 目前对抗胰腺炎的治疗选择显示有效性有限,这凸显了迫切需要新的治疗方法.
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