低血症与COVID-19患者的结局之间的关联:一项回顾性研究
Bhagwan Singh Patidar1, Tapasyapreeti Mukhopadhyay1, Arulselvi Subramanian1
1Department of Laboratory Medicine, Jai Prakash Narayan Apex Trauma Center, All India Institute of Medical Sciences, New Delhi, India.
Journal of laboratory physicians
|June 16, 2023
概括
低血症或低水平与2019年冠状病毒病 (COVID-19) 患者的严重程度和死亡率的增加有关. 这一发现强调了监测水平在COVID-19护理中的重要性.
科学领域:
- * * 医学研究 医学研究
- * 传染病 传染病
- * 关键护理医学 关键护理医学
背景情况:
- *已知在严重急性呼吸系统综合征-冠状病毒-2和中东呼吸系统综合征冠状病毒病理生理学中的作用.
- *关于2019年新冠肺炎 (COVID-19) 冠状病毒病 (COVID-19) 中的低血症 (低水平) 以及其对疾病严重程度和患者结局的影响的数据有限.
研究的目的:
- * 评估COVID-19患者呈现低血症的临床特征.
- * 调查低血症和COVID-19疾病严重程度之间的关联.
- * 确定低血症对COVID-19患者死亡率的影响.
主要方法:
- *回顾性研究分析了COVID-19患者的人口,临床和实验室数据.
- * 根据对白蛋白进行校正的水平,将患者分为正常血和低血组.
- *主要测量结果是死亡率.
主要成果:
- * 低血症COVID-19患者年轻,严重感染,并发病和呼吸机支持率较高.
- * 低血症组的死亡率明显高 (33.63%).
- *低血症与较低的血红蛋白,血红素,红细胞计数以及较高的绝对中性粒细胞计数 (ANC) 和中性粒细胞与淋巴细胞比率 (NLR) 相相关.
结论:
- *低血症与疾病严重程度的增加,更高的呼吸器需求和COVID-19患者的死亡率增加有关.
- *与白蛋白校正的水平与各种血液学和蛋白质标记物有显著的相关性.
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