性别对心房移除结果的影响,使用倾向性得分匹配分析
Mohammed Al-Sadawi1, Faisal Aslam1, Chad Gier1
1Cardiovascular Department, Stony Brook Medicine, Stony Brook, New York.
Heart rhythm O2
|June 16, 2023
概括
性别不会影响心房动 (AF) 除结果. 这项研究发现,经过AF切除的男性和女性患者之间的AF复发或并发症没有显著差异,这表明安全性和疗效相似.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医学研究 医学研究
背景情况:
- 患有心房的女性可能会出现更高的复发率和非肺静脉 (非PV) 触发因素.
- 性别对AF切除策略和结果的影响需要进一步调查.
研究的目的:
- 评估性别对心房动 (AF) 废除手术结果的影响.
主要方法:
- 从2013年1月到2021年7月,对1412名患者 (34%为女性) 的1568例AF剥离进行了分析.
- 随访至少6个月,以评估AF复发,并发症和住院情况.
- 用多变量逻辑回归和倾向得分匹配 (PSM) 来进行分析.
主要成果:
- 两性之间没有观察到AF复发率的显著差异 (HR 1.15;95% CI 0.92-1.43;P >.05).
- 在PSM之后,两性之间没有发现AF复发或与程序相关的并发症的差异.
- 持续性AF (HR 1.54) 和70岁以上的年龄 (HR 1.03) 的病史与复发和需要额外的程序有关,独立于性别.
结论:
- 性别似乎不会影响AF切除的整体安全性或疗效.
- 持续性AF和老年是复发和需要进一步干预的关键预测因素.
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