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Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
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老年评估工具在患有胃肠道癌症的老年患者中的临床效用
Ayako Doi1, Takuro Mizukami1,2, Hiroyuki Takeda1
1St. Marianna University School of Medicine, Department of Clinical Oncology, Kawasaki, Japan.
Frontiers in oncology
|June 16, 2023
概括
老年8 (G8) 评分和日常生活的仪器活动 (IADL) 可以预测老年肠胃癌患者的生存率. 一个G8分数截止值为11和正常的IADL对于预测整体生存是有用的.
科学领域:
- 老年瘤学是一门老年瘤学专业.
- 胃肠道瘤学 胃肠道瘤学
- 临床评估工具 临床评估工具
背景情况:
- 建议使用老年8 (G8) 和日常生活工具活动 (IADL) 来预测老年癌症患者的结果.
- 它们在患有胃肠道 (GI) 癌症,包括胃癌 (GC) 和胰腺癌 (PC) 的营养不良老年患者的临床实用性尚未得到充分证实.
研究的目的:
- 评估G8和IADL在预测肠胃癌老年患者整体存活率 (OS) 和严重不良事件 (SAE) 的临床实用性.
- 在这个特定的患者群体中确定G8和IADL的适当切割值.
主要方法:
- 追溯研究包括207名年龄≥65岁的GC,PC和结直肠癌 (CRC) 患者,他们在2018年4月至2020年3月期间接受治疗.
- 在首次诊断时使用G8问卷;在患有晚期/无法切除瘤的患者中,评估了G8/IADL得分与安全/OS之间的关联.
主要成果:
- 患者的中位年龄为75岁,G8平均分数为10.5. 正常G8得分 (>14) 的比率为6.8%.
- 在标准G8切线14和SAE或OS之间没有明确的关联.
- 在G8>11 (19.3个月) 与G8 ≤11 (10.5个月) (p=0.0017) 的患者中,OS显著更长.
- 在正常IADL (17.6个月) 与异常IADL (11.4个月) (p=0.049) 的患者中,OS显著更好.
结论:
- 14的标准G8截止值在临床上对于预测老年肠道癌症患者的OS或SAE并不有用.
- 一个G8切割值11和IADL状态似乎有用预测OS在老年患者的胃肠道癌,包括GC和PC.
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