与静脉静脉外体膜氧化疗法死亡率相关的预测因素
Elena Neumann1, Sebastian D Sahli1, Alexander Kaserer1
1Institute of Anesthesiology, University and University Hospital Zurich, Zurich, Switzerland.
Journal of thoracic disease
|June 16, 2023
概括
静脉静脉外体膜氧化 (V-V ECMO) 的住院死亡率仍然很高,并没有随着时间的推移而有所改善. 死亡率的主要预测因素包括晚年,肝衰竭和输血产品.
科学领域:
- 关键护理医学 关键护理医学
- 支持心肺血管的支持.
- 移植医学 移植医学
背景情况:
- 静脉静脉外体膜氧化 (V-V ECMO) 的使用在ARDS和肺移植后并发症等疾病中增加了.
- 应用包括急性呼吸系统应急综合征 (ARDS),桥梁到肺移植和初级移植功能障碍.
研究的目的:
- 调查接受V-V ECMO治疗的成年患者的住院死亡率.
- 确定与V-V ECMO相关死亡率相关的独立预测因素.
主要方法:
- 从2007年到2019年在瑞士ECMO中心对221个成年V-VECMO病例进行了回顾性分析.
- 使用后勤回归建模来确定死亡率的显著预测因素.
主要成果:
- 整体住院死亡率为37.6%,在13年的研究期间没有显著变化.
- 死亡率的独立预测因素包括老年 (OR 1.05),新发现的肝衰竭 (OR 4.83),红细胞输血 (OR 1.91) 和血小板度输血 (OR 1.93).
结论:
- 对于V-V ECMO的住院死亡率仍然很高,随着时间的推移没有观察到明显的改善.
- 年龄,肝衰竭和输血产品是死亡率的重要预测因素.
- 将这些预测因素纳入V-V ECMO决策可能会改善患者的治疗结果.
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