在手术期间30%与80%氧气度的血液动力学影响:一个探索性分析
Christian Reiterer1,2, Edith Fleischmann1,2, Barbara Kabon1,2
1Department of Anesthesia, Intensive Care Medicine and Pain Medicine, Medical University of Vienna, Vienna, Austria.
Frontiers in medicine
|June 16, 2023
概括
在手术期间的高氧水平并没有显著改变麻醉患者的血压或心率. 这表明补充氧气.
科学领域:
- 麻醉学 麻醉学
- 心血管生理学心血管生理学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 补充氧气通常会增加血管阻力和血压.
- 这种效应在各种患者群体中得到证实,包括心脏病和败血症患者.
- 它对麻醉外科手术患者的影响仍未得到调查.
研究的目的:
- 为了研究手术期间不同氧气度的血液动力学影响.
- 为了确定高吸入氧气 (80%) 是否与标准氧气 (30%) 相比,影响手术内血压和心率.
主要方法:
- 一项随机对照试验的探索性分析,涉及258名接受重大腹部手术的患者.
- 在外科手术期间,患者接受了80%或30%的启发氧气.
- 持续监测动脉血压和心率;计算时间加权平均值 (TWA) 和平均真实变化率 (ARV).
主要成果:
- 80%和30%氧气组之间的平均动脉压TWA没有显著差异 (80 mmHg与81 mmHg).
- 在80%和30%的氧气组之间,心率TWA没有显著差异 (65bpm vs 64bpm).
- 两组之间没有观察到对血压或心率的ARV有显著差异.
结论:
- 与之前的发现不同的是,80%的氧气在麻醉外科手术患者中没有显著增加血压或降低心率.
- 在这种特定的患者群体中,补充氧气的血液动力学效应似乎可以忽略不计.
- 可能需要进一步的研究来证实这些发现在不同的外科设置.
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