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针对局部晚期结肠癌的结肠切除术后复发:发展中国家的经验

Artur M Sahakyan^1,2, Andranik Aleksanyan^1,3, Hovhannes Batikyan¹

¹Department of Surgery N1, Yerevan State Medical University After M. Heratsi, Yerevan, Armenia.

Indian journal of surgical oncology

|June 16, 2023

概括

确定手术后结肠癌复发的危险因素至关重要. 瘤阶段,结节阶段和淋巴结产量是局部晚期结肠癌 (LACC) 复发的关键预测因素.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
胃肠病学胃肠病学

背景情况:

对于局部晚期结肠癌 (LACC) 的治愈切除术后疾病复发的风险因素尚未确定.
关于这些预后因素,文献中存在相互矛盾的结果.
发展中国家对多式模式癌症治疗的获取有限可能会影响复发模式.

研究的目的:

调查与LACC治疗切除后疾病复发相关的因素.
在这个患者群体中分析复发类型和无复发存活率.
为了了解医疗保健系统中的复发风险,医疗保健系统的多式联络治疗可用性有限.

主要方法:

在2004年至2018年期间,对118名为LACC进行了治疗性结肠切除的患者进行了回顾性分析.
从前性维护的数据库中收集的数据.
进行多变量和单变量分析以确定显著因素.

主要成果:

在52.5%的患者中观察到疾病复发.
多变量分析将瘤阶段,结节阶段和淋巴结与疾病复发联系起来.
局部复发,远程转移和腹癌发生在6.8%,25.4%和20.3%的患者中.
在多变量模型中,瘤阶段是无复发生存的唯一独立预测因素.

结论:

淋巴结产量,瘤阶段和结节阶段与LACC治疗切除后的复发有显著的相关性.
瘤阶段是影响无复发生存的关键因素.
这些发现对于在资源有限的环境中管理LACC具有重要意义.

关键词:

腺癌是什么?腺癌是什么?腺癌是什么?进行大肠切除术 (colectomy).科伦·科伦 (Colon Colon) 是指一个结肠.复发情况复发情况

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