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在外围神经再生中,为脱细胞化神经异体移植进行物理处理

Ming-Wei Hsu¹, Szu-Han Chen^1,2,3, Wan-Ling Tseng⁴

¹Division of Plastic and Reconstructive Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Frontiers in bioengineering and biotechnology

|June 16, 2023

概括

物理方法为神经异细胞移植提供了高效的脱细胞化,这对于外围神经再生至关重要. 本综述探讨了清除细胞碎片和维持神经架构的物理过程,解决未来的挑战.

科学领域:

生物材料科学生物材料科学
再生医学是一种再生医学.
组织工程是组织工程.

背景情况:

自主神经移植是神经损伤的标准,但存在诸如可用性和供体部位问题等局限性.
目前的合成或生物替代品显示出不一致的临床结果.
仿生神经异种移植提供了一个替代方案,脱细胞化是成功的关键.

研究的目的:

审查最近在神经外移植脱细胞化物理方法方面的进展.
评估物理过程对移除细胞碎片和异种移植结构完整性的影响.
为了比较物理脱细胞化技术的优缺点.

主要方法:

对神经异细胞移植的物理脱细胞化技术的当前文献的综述.
对专注于细胞碎片清除效率的研究进行分析.
评估保存神经支架本土结构的方法.

主要成果:

物理方法可以有效地清除神经外移植中的细胞碎片.
某些物理过程保持本地神经架构的结构完整性.
各种物理脱细胞化方法的优缺点的比较.

结论:

物理脱细胞化是神经异细胞移植的一个有前途的方法,它补充了化学和酶方法.
优化物理过程对于有效的外围神经再生至关重要.
需要多学科的方法来克服挑战,并利用脱细胞神经异种移植的发展机会.

关键词:

脱细胞化的神经异体移植.结解的方法沉浸和激动的浸入和激动.perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion perfusion 这是一个非常重要的方法,它可以让一个人成为一个非常重要的角色,一个非常重要的角色,一个非常重要的角色,一个非常重要的角色,一个非常重要的角色,一个非常重要的角色,一个非常重要的角色,一个非常重要的角色外围神经的再生和再生物理处理物理处理超声波的使用方法超临界流体的超临界流体

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