鱼类,玉米和乳清蛋白水解剂对高级糖化最终产品 (AGEs) 的潜在抑制作用
Faezeh Arasteh1, Mohsen Barzegar1, Hassan Ahmadi Gavlighi1
1Department of Food Science and Technology, Faculty of Agriculture Tarbiat Modares University Tehran Iran.
Food science & nutrition
|June 16, 2023
概括
鱼蛋白水解剂 (FPH) 有效地抑制了先进的糖化最终产品 (AGEs) 的形成,显示了近99%的抑制. 这项研究突出了FPH.
科学领域:
- 食品化学 食品化学
- 生物化学 生物化学
- 营养科学 营养科学
背景情况:
- 在梅拉德反应过程中形成先进的糖化最终产品 (AGEs).
- 来自植物或动物来源的天然水解剂可能会抑制AGE的形成.
- 研究蛋白质水解剂的抗糖化潜力对于功能性食品的开发至关重要.
研究的目的:
- 评估鱼蛋白水解盐 (FPH),玉米蛋白水解盐 (MPH) 和乳清蛋白水解盐的抗糖化潜力.
- 在各种模型系统中比较这些水解剂对AGE形成的抑制作用.
- 确定具有抗糖化特性的功能性食品成分的有前途的自然来源.
主要方法:
- 使用了四个模型系统:牛血清白蛋白 (BSA) 与葡萄糖,果糖,醇和高果糖玉米糖 (HFCS).
- 在37°C的温度下将反应混合物化七天.
- 通过测量光强度来量化AGE的形成.
主要成果:
- 鱼蛋白水解剂 (FPH) 显示出最高的抑制作用,达到0.16%的约99%的抑制.
- 与FPH相比,玉米蛋白水解剂 (MPH) 的抗糖化活性较低.
- 乳清蛋白水解酸显示出最弱的抑制活性,与其较低的水解度相关.
结论:
- 蛋白质水解剂,特别是FPH,具有显著的抗糖化潜力.
- 可以推FPH用于开发旨在减少AGE积累的功能性食品.
- 对天然化物的进一步研究可能会导致新的策略来管理与糖化相关的健康问题.
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