在40-79岁的成年人中,个别营养素和血清克洛托水平
Sergej M Ostojic1, Elisabet R Hillesund1, Nina C Øverby1
1Department of Nutrition and Public Health University of Agder Kristiansand Norway.
Food science & nutrition
|June 16, 2023
概括
碳水化合物和糖类等特定营养素与较高的抗衰老克洛托蛋白水平有关. 这项研究探讨了Klotho与个别营养素的关联,表明饮食影响衰老生物标志物.
科学领域:
- 营养科学 营养科学
- 生物化学 生物化学
- 老年学是一门学科.
背景情况:
- 循环的克洛托蛋白水平与衰老和各种健康结果有关.
- 地中海饮食和坚果摄入等饮食模式与克洛托有积极的关联.
- 单个营养素对克洛托水平的影响仍未得到充分研究.
研究的目的:
- 调查个人宏观和微量营养素以及非营养食品成分与循环Klotho水平之间的关联.
- 分析与美国成年人血清克洛托度相关的饮食摄入数据.
主要方法:
- 分析了2015-2016年国家健康和营养检查调查 (NHANES) 的数据.
- 使用相对于总能量摄入的营养密度方法计算营养素/食品成分摄入量.
- 在2637名年龄在40-79岁的美国成年人样本中测量血清Klotho度.
主要成果:
- 高血清克洛托度与增加的碳水化合物,总糖,食纤维,维生素D,总叶酸盐和铜的摄入量显著相关.
- 回归分析显示,Klotho水平与碳水化合物,酒精,总糖,食纤维和酸盐之间存在显著的关联.
- 在调整了年龄和性别后,碳水化合物,总糖和酒精仍然与Klotho水平有显著的关联.
结论:
- 单个饮食营养素和非营养食品成分与循环的Klotho水平有关.
- 饮食摄入量,特别是碳水化合物和糖,可能在调节Klotho活性方面发挥作用.
- 需要进一步的研究来确定特定的饮食成分与Klotho功能之间的因果关系.
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