在Hidradenitis Suppurativa患者中COVID-19感染:一项回顾性研究
Devea R De1, Jonathan W Rick2, Terri Shih3
1Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
Skin appendage disorders
|June 16, 2023
概括
患有COVID-19的Hidradenitis suppurativa (HS) 患者没有比没有HS的患者更糟糕的结果. 这表明HS不是COVID-19严重并发症的重要风险因素.
科学领域:
- 医学研究 医学研究
- 传染病流行病学传染病流行病学
- 皮肤病学 皮肤病学
背景情况:
- 补腺炎 (HS) 是一种慢性炎症性皮肤疾病.
- HS与增加COVID-19严重性风险的并发症有关.
- HS对COVID-19结果的影响需要调查.
研究的目的:
- 评估HS患者的人口统计和COVID-19结果.
- 为了比较HS患者和匹配的对照组之间的COVID-19严重程度和并发症.
主要方法:
- 对58名患有COVID-19的HS患者 (HS+/COVID+) 和没有HS的匹配对照 (HS-/COVID+) 的回顾性图表审查.
- 收集的数据包括人口统计,并发症,疫苗接种状态和COVID-19结果.
- 费舍尔的精确测试分析了风险因素和结果;p<0.05是显著的.
主要成果:
- 在HS/COVID+患者中,心血管疾病 (51%对24%) 和怀孕 (23%对4%) 的发病率较高.
- 在HS-/COVID+患者中,COVID-19并发症 (35%vs. 7%) 和治疗 (37%vs. 7%) 更频繁.
- 疫苗接种率在各组之间是相似的 (6%对5%).
结论:
- 对于严重的COVID-19结果,HS本身可能不是一个独立的风险因素.
- 伴随性疾病,而不是HS,似乎在受影响的患者中驱动严重的COVID-19.
- 需要进一步的研究来了解HS和COVID-19的相互作用.
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