相关实验视频
Updated: Jul 26, 2025

04:27
Intratracheal Instillation of Stem Cells in Term Neonatal Rats
Published on: May 4, 2020
5.7K
红细胞输血与支气管肺功能障碍之间的关联:系统性审查和元分析
Li Tang1,2,3, Ting Ting Zhu2,3, Jing Zhao2,3
1Department of Pediatrics Hematology and Oncology Nursing, West China Second University Hospital, Sichuan University, Chengdu, China.
Frontiers in pediatrics
|June 16, 2023
概括
红细胞输血 (RBCT) 与新生儿的支气管肺功能障碍症 (BPD) 有显著的关联. 然而,研究中的大量异质性意味着确切的关系需要进一步调查.
科学领域:
- 新生儿医学 新生儿医学
- 儿科肺病学 儿科肺病学
- 血液学 血液学 血液学
背景情况:
- 支气管肺功能障碍症 (BPD) 是早产婴儿发病的一个重要原因.
- 红细胞输血 (RBCT) 在新生儿中很常见,但它们与BPD的关联是有争议的.
研究的目的:
- 为了确定红细胞输血和新生儿支气管肺功能障碍症之间的关联.
- 通过系统审查和元分析来综合现有证据.
主要方法:
- 对病例控制,横截面和队列研究的系统审查和元分析.
- 在PubMed,Embase和Web of Science的文献搜索到2022年5月1日.
- 纽卡斯尔-太华尺度用于方法质量评估;随机效应模型用于数据聚合.
主要成果:
- 分析了21项研究,包括1476名BPD患者和6567名对照患者.
- 在RBCT和BPD之间发现了显著的关联 (调整后OR:5.11;95%CI:3.11-8.4).
- 观察到实质性的异质性,可能由输血程度解释.
结论:
- 建议BPD和RBCT之间的关联,但由于显著的异质性,仍然不清楚.
- 需要进一步的精心设计的研究来澄清这种关系.
相关概念视频
Rh Blood Group
1.6K
The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
1.6K
Blood Transfusion and Agglutination
10.9K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.9K
Blood Transfusion
624
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
624
Bone Marrow Sampling and Transplants
363
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
363
Acute Respiratory Failure-II
287
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
287
Pulmonary Cycle: Exhalation
1.7K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.7K

