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Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
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在癌症免疫治疗中修复DNA不匹配

Junhong Guan1, Guo-Min Li2

  • 1Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou, Gansu 730030, China.

NAR cancer
|June 16, 2023
PubMed
概括

具有缺陷DNA不匹配修复 (dMMR) 的瘤对免疫检查点抑制剂 (ICI) 反应良好. 本综述探讨了dMMR免疫疗法机制,耐药性问题以及改善MSI瘤治疗有效性的策略.

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