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长度母体血液动力学评估在不复杂的双胞胎怀孕根据chorionicity:生理心血管功能障碍在单胞胎双胞胎怀孕

D Farsetti^1,2, F Pometti¹, G P Novelli³

¹Department of Surgical Sciences, University of Rome Tor Vergata, Rome, Italy.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology

|June 16, 2023

概括

双胞胎怀孕与单胞胎怀孕相比,单胞胎 (MC) 和双胞胎 (DC) 怀孕之间的母体血液动力学有所不同. 双胞胎MC表现出明显的心血管变化,特别是在第二和第三个三个月,表明胆管性影响母亲的心脏功能.

科学领域:

产科和妇科产科和妇科
孕产妇和胎儿医学孕产妇和胎儿医学
心血管生理学心血管生理学

背景情况:

母亲的心脏功能对于胎盘发育至关重要.
双胞胎怀孕比单独怀孕更明显的血液动力学变化.
胆性可能会影响孕妇在怀孕期间的心血管适应.

研究的目的:

纵向比较未复杂的双胞胎怀孕中的双胞胎 (DC) 和单胞胎 (MC) 双胞胎怀孕中的母体血动力学变化.
将这些变化与单独怀孕中观察到的变化进行比较.

主要方法:

包括40个MC双子妊娠,35个DC双子妊娠和294个单子妊娠.
使用超声波心脏输出监测器 (USCOM®) 进行血液动力学评估,怀孕11-15周,20-24周和29-33周.
测量参数包括平均动脉压 (MAP),中风体积 (SV),心脏输出 (CO) 和全身血管阻力 (SVR).

主要成果:

第一季度:DC和MC双胞胎的MAP,SVR较低,CO和SV比单胞胎高.
第二个三个月:MC双胞胎与DC双胞胎相比,母亲的CO和心脏指数 (CI) 显著更高.
第三个三个月:MC双胞胎的潜在动能比率 (PKR) 和全身血管阻力指数 (SVRI) 较高,但 SV,中风体积指数 (SVI) 和内托普指数 (INO) 与单身双胞胎相比较低.

结论:

在没有并发症的双胞胎怀孕中,母亲的心血管功能发生显著变化,受表性影响.
从MC和DC双胞胎的头三个月开始,血液动力学变化就很明显.
与DC双胞胎和单胞胎相比,MC双胞胎怀孕显示出一个明显的模式,在第二个三个月内增加心脏输出量,然后在第三个月内降低心血管性能.

关键词:

心血管功能是什么心血管功能双胞胎怀孕是二子的怀孕.孕产妇的血液动力学双胞胎怀孕是一种单双胞胎怀孕.

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