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出生史和心血管疾病的风险 在显著肥胖的年轻人中
Sara K Hurley1, Diane Vizthum1, Kirstie Ducharme-Smith2
1School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Clinical pediatrics
|June 16, 2023
概括
过早生育并不能独立预测肥胖儿童的高血压或心脏异常. 促进健康的生活方式是儿童心血管健康的关键.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管健康 心血管健康
- 新生儿研究新生儿研究
背景情况:
- 过早出生的儿童面临高血压和心血管疾病 (CVD) 的终身风险增加.
- 儿童肥胖问题越来越令人担忧,可能会加剧心血管疾病风险.
研究的目的:
- 为了研究早产和心血管疾病风险因素在儿童肥胖和高血压之间的关联.
- 为了确定饮食中的摄入量是否会改变这些关联.
主要方法:
- 多变量回归分析用于评估早产 (妊娠年龄<37周;低出生体重<2.5公斤) 和高血压,左心室质量指数 (LVMI) 和左心室缩 (LVH) 之间的关系.
- 通过饮食中的摄入量对90名患有肥胖和高血压的儿童进行了效果调整的研究.
主要成果:
- 在这个队列中,早产 (早期妊娠年龄/低出生体重) 并不是高血压,LVMI或LVH的独立预测因素.
- 饮食中的摄入量没有显示出对早产和心血管疾病风险因素之间的关联有显著影响的修改.
结论:
- 与早产相关的心血管疾病风险增加在具有特定心脏代谢特征的儿童中可能不那么明显.
- 通过促进心脏健康的生活方式来预防儿童肥胖对于长期的心血管健康至关重要.
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