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Updated: Jul 26, 2025

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具有多个上皮抗原表达和PABPC1的ALK阳性大B细胞淋巴瘤:ALK融合:一种新的分子变异

Jian Jeff Fu1, Anjali Seth1, Nadia Ali2

  • 1Department of Pathology and Laboratory Medicine, Temple University Health System.

The American journal of surgical pathology
|June 16, 2023
PubMed
概括

阳性大B细胞淋巴瘤 (LBCL) 是罕见的和积极的. 这种病例突出显示了异常的表皮标记物表达和一种新的PABPC1::ALK融合,有助于诊断这种具有挑战性的淋巴瘤.

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Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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