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在儿科肝移植期间的手术内液体输送量和术后的结果:多中心分析
Proshad N Efune1,2, Matthew J Hoyt3, Rita Saynhalath1,2
1Division of Pediatric Anesthesia, Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Paediatric anaesthesia
|June 16, 2023
概括
在手术期间注射液体与儿科肝移植后机械通风的持续时间有很弱的相关性. 需要对其他可修改因素进行进一步的研究,以改善这些脆弱患者的治疗结果.
科学领域:
- 儿科手术 儿科手术
- 移植医学 移植医学 移植医学
- 关键护理医学 关键护理医学
背景情况:
- 输液在儿科肝移植中至关重要,可以影响患者的治疗结果.
- 了解手术内流体体积对术后恢复的影响至关重要.
研究的目的:
- 评估在接受肝移植的儿童手术后机械通风量和术后机械通风持续时间之间的关系.
- 探索二次结果,包括重症监护室 (ICU) 和住院时间.
主要方法:
- 这是一项多中心的回顾性队列研究,涉及286名儿科肝移植患者.
- 术内液体的使用与患者的体重和麻醉的持续时间有关.
- 为了确定相关性,进行了单变量和阶段线性回归分析.
主要成果:
- 在手术期间输入液体和术后机械通风的持续时间之间发现了微弱的相关性 (r2 = .161,p = .04).
- 影响通风持续时间的其他重要因素包括移植中心和移植后使用开放腹部切口.
- 平均通风持续时间为10.8小时,ICU停留时间为4.3天,住院时间为13.6天.
结论:
- 在手术期间注射液体与儿科肝移植后机械通风持续时间的相关性有限,很弱.
- 探索其他可修改的因素是必要的,以提高儿科肝移植接受者的术后结果.
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