静止行为的生理学
Ana J Pinto1,2, Audrey Bergouignan1,3, Paddy C Dempsey4,5,6,7
1Division of Endocrinology, Metabolism, and Diabetes, Anschutz Health and Wellness Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Physiological reviews
|June 16, 2023
概括
减少久坐行为 (SB) 提供了适度的健康益处,改善体重,血糖和心血管标志物. 需要进一步的研究来了解SB对不同人群的分子影响.
科学领域:
- 生理学 生理学 生理学
- 运动科学 运动科学
- 公共卫生 公共卫生
背景情况:
- 久坐式行为 (SB) 涉及在坐着或躺着时消耗较少的能量.
- 用床上休息和减少体力活动等模型研究SB的生理影响.
- 过度的SB会对新陈代谢,心血管健康和身体组成产生负面影响.
研究的目的:
- 检查物理证据,将久坐不动行为与各种健康结果联系起来.
- 审查减少或中断长时间的久坐时间的影响.
- 确定不同人群中关于SB和健康的研究缺口.
主要方法:
- 实验模型的分析:床上休息,固定,减少步数和SB中断.
- 对多个系统的生理数据的审查:代谢,心血管,肌肉骨,神经和免疫系统.
- 综合了对成年人,老年人,儿童和青少年的研究结果.
主要成果:
- 长时间的SB与胰岛素耐药性,血管功能障碍,健康状况下降以及身体脂肪和炎症增加有关.
- 减少/中断SB的干预措施在成人和老年人中显示出小但潜在的有意义的好处.
- 观察到的好处包括改善体重,腰围,体脂,血糖控制,血脂,血压和血管功能.
- 对其他健康结果和儿童/青少年的证据更为有限.
结论:
- 减少久坐行为会带来适度的健康改善,特别是在成年人和老年人中.
- 对SB适应的基础分子机制进行进一步的研究是有必要的.
- 针对不同人群,需要量身定制的干预措施,将减少SB和增加体育活动结合起来.
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