在50岁后的认知变量中,队列变化和性别差异在英国长度老龄化研究中的认知变量
Patrick O'Keefe1, Graciela Muniz-Terrera2, Stacey Voll3
1Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA.
概括
认知衰老显著影响口语流和记忆,观察到显著的性别和出生队列差异. 晚出生的队伍通常在衰老中表现出更好的认知功能.
科学领域:
- 老年学是指老年学的学科.
- 认知神经科学 认知神经科学
- 人口健康 人口健康
背景情况:
- 认知衰老是健康衰老的一个关键方面,具有显著的个体变化.
- 了解认知轨迹中的性别和出生队列差异对于有针对性的干预措施至关重要.
- 以前的研究表明认知衰老的变化,但需要在多个队伍中进行全面的建模.
研究的目的:
- 模拟从中到晚年的人生认知衰老轨迹.
- 估计初始认知水平和衰老速度的性别和出生队列差异.
- 分析随着时间的推移在一个大,多队列样本中的认知变化.
主要方法:
- 利用了英语长度老化研究 (n=76,014) 的9个波 (2002-2019) 的数据.
- 评估认知功能,包括口头流利,立即回忆,延迟回忆和定向.
- 采用贝叶斯逻辑增长曲线模型来分析认知轨迹.
主要成果:
- 观察到大量认知能力下降的语言流性,立即回忆 (约. 30%的损失),以及在52-89岁之间延迟回忆 (男性40%,女性50%).
- 导向显示了最小的衰老效应 (<10%的变化).
- 发现了显著的出生队列效应,在1930-1950年间出生的个体表现出特别改善的初始认知能力,有利于晚期出生的队列.
结论:
- 认知衰老的轨迹因认知领域,性别和出生队伍而异.
- 晚出生的人群通常具有更高的初始认知能力,这表明社会或环境的影响.
- 研究结果强调,需要个性化方法来治疗老年人群的认知健康.
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