抑制性控制和酒精使用史预测创伤后应激障碍症状的变化
Joseph DeGutis1, Sam Agnoli1, Charles E Gaudet2
1Translational Research Center for Traumatic Brain Injury and Stress Disorders, VA Boston Healthcare System.
Neuropsychology
|June 16, 2023
概括
慢性创伤后应激障碍 (PTSD) 的预测因素包括较低的抑制控制和酒精使用史. 这些因素似乎稳定,可能表明在被诊断患有PTSD的退伍军人中存在风险或弹性.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 创伤后应激障碍 (PTSD) 是一种使人衰弱的疾病,可以慢性化.
- 预测PTSD症状轨迹的预测因素,特别是在被诊断出来的个体中,需要进一步阐明.
研究的目的:
- 在9/11事件后的退伍军人中调查PTSD症状变化的预测因子,在2年的时间里诊断出患有PTSD的退伍军人.
- 检查基线认知功能,酒精使用史和PTSD症状慢性之间的关系.
主要方法:
- 一组187名患有PTSD的9/11后退伍军人接受了两次临床和认知评估,大约两年间隔.
- 评估PTSD症状,抑制控制 (色词抑制,抑制/切换),其他执行功能,以及终身饮酒史.
主要成果:
- 较大的PTSD症状减少与较低的终身酒精消费和更好的基线抑制控制相关.
- 患有改善,慢性或恶化的PTSD症状的退伍军人在基线抑制控制和饮酒史上有显著差异.
- 创伤后应激障碍症状的变化与抑制控制或酒精使用的变化无关.
结论:
- 抑制性控制和酒精使用史似乎是被诊断为退伍军人的PTSD慢性病的稳定风险或弹性因素.
- 这些发现强调了这些稳定因素在理解PTSD轨迹方面的重要性.
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