据说14世纪的食物传播查加斯病爆发,墨西哥
1Artemis One Health Research Foundation, Delft, The Netherlands.
Vector borne and zoonotic diseases (Larchmont, N.Y.)
|June 16, 2023
概括
14世纪在科约阿坎的一次流行病可能是食物传播的查加斯病. 这种由Trypanosoma cruzi引起的寄生虫疾病,可能在鱼类供应不足时通过食用感染的虫传播.
科学领域:
- 古病理学 古病理学
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 大约在1330年,墨西哥科约阿坎发生了一场严重的流行病,其特点是高发病率和死亡率.
- 历史记录描述了包括,出血性腹和高死亡率在内的症状,特别是在年轻人和老年人中.
- 这种疾病传统上归因于营养不足.
研究的目的:
- 为了调查14世纪科约阿坎疫情的潜在病因.
- 评估疫情是由食物传播的查加斯病引起的假设.
主要方法:
- 分析历史年代记者关于疫情临床表现和情况的叙述.
- 观察到的症状和流行病学背景与查加斯病已知的特征进行比较.
- 在该地区确定Trypanosoma cruzi的潜在储存库.
主要成果:
- 疫情的临床特征 (,出血性腹) 和背景 (食物供应中断) 与食物传播的查加斯病相吻合.
- 子 (Didelphis spp.) 是一个类型. 已被确定为Trypanosoma cruzi的潜在储存库和可信的替代食物来源.
- 传统的营养缺乏症解释并不能完全解释观察到的病理.
结论:
- 1330年左右的科约阿坎疫情与食物传播的查加斯病爆发非常一致.
- 吃受感染的鱼是一种可能的传播途径,特别是在食物短缺期间.
- 重新评估具有类似表现的历史流行病是有必要的,以考虑寄生虫感染.
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