持有人巴氏杀菌和UV-C辐射对母乳中菌体标位的影响
Lisa F Stinson1, Donna T Geddes1, Lucy L Furfaro2,3
1School of Molecular Sciences, The University of Western Australia, Perth 6009, Australia.
FEMS microbiology letters
|June 16, 2023
概括
持有人消毒 (HP) 和紫外线C辐射 (UV-C) 在人乳菌体上进行了测试. 紫外线有效地禁用了耐热和热敏菌体,而HP对耐热菌体无效.
科学领域:
- 微生物学 微生物学
- 婴儿营养 婴儿营养
- 食品科学 食品科学 食品科学
背景情况:
- 人母乳对于婴儿营养至关重要,因为它含有生物活性化合物和微生物.
- 纯化供体牛奶是一种替代方案,特别是对于早产婴儿, Holder 纯化 (HP) 是安全标准.
- 牛奶中的菌体 (菌体) 可能会影响婴儿肠道微生物群,但对它们的巴氏杀菌效应尚不清楚.
研究的目的:
- 评估Holder消毒 (HP) 和紫外线C辐射 (UV-C) 对母乳中菌体标位的影响.
- 调查UV-C作为HP替代品的疗效,用于在捐赠奶中的菌体失活.
主要方法:
- 十个捐赠人母乳样本被接种了耐热的大肠杆菌菌体 (T4) 和热敏的金黄色葡萄球菌菌体 (BYJ20).
- 样品经过持有者消毒 (HP) 和紫外线-C (UV-C) 辐射.
- 在乳和水对照中测量了菌体标位处理后.
主要成果:
- 紫外线辐射有效地使母乳和水控制中的T4和BYJ20菌体失活.
- 持有人巴氏杀菌 (HP) 在不激活耐热T4菌体方面是无效的.
- 数据表明,UV-C可能会消除可能影响早产婴儿肠道殖民的菌体.
结论:
- 紫外线-C辐射显示出作为一种在捐赠人母乳中使细菌菌体失活的方法具有前景.
- HP不足以消除所有类型的菌体,特别是耐热菌株.
- 需要进一步的研究来评估UV-C对人类牛奶中发现的更广泛的菌体的疗效.
相关概念视频
Physical Methods for Controlling Microbial Growth: Temperature
149
Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
149
Lysogenic Cycle of Bacteriophages
62.6K
In contrast to the lytic cycle, phages infecting bacteria via the lysogenic cycle do not immediately kill their host cell. Instead, they combine their genome with the host genome, allowing the bacteria to replicate the phage DNA along with the bacterial genome. The incorporated copy of the phage genome is called the prophage. Some prophages can re-activate and enter the lytic cycle. This often occurs in response to a perturbation, such as DNA damage, but can also transpire in the absence of...
62.6K
Lytic Cycle of Bacteriophages
71.1K
Bacteriophages, also known as phages, are specialized viruses that infect bacteria. A key characteristic of phages is their distinctive “head-tail” morphology. A phage begins the infection process (i.e., lytic cycle) by attaching to the outside of a bacterial cell. Attachment is accomplished via proteins in the phage tail that bind to specific receptor proteins on the outer surface of the bacterium. The tail injects the phage’s DNA genome into the bacterial cytoplasm. In the...
71.1K


