中国急性心力衰竭患者接种流感疫苗的集群随机试验:一种混合方法可行性研究
Rong Liu1,2, Xin Du1,2,3, Anushka Patel2
1Heart Health Research Center (HHRC), Beijing, China.
PLOS global public health
|June 16, 2023
概括
实施医院流感疫苗接种策略显著增加了中国心力衰竭患者的疫苗覆盖率. 这种方法被证明是可行的和可接受的,提供了一种有希望的方法来提高这一脆弱人群的疫苗接种率.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 在心力衰竭 (HF) 患者中,低流感疫苗覆盖率 (VCR) 阻碍了心血管结果的预防.
- 需要有效的疫苗接种策略,特别是在像中国这样的地区.
研究的目的:
- 评估中国急性心力衰竭患者在医院内流感疫苗接种推广战略的可行性.
- 为了为混合有效性实施试验的设计提供信息.
主要方法:
- 一个集群随机试验试验,涉及中国河南省11家医院.
- 混合方法评估,包括采访51个关键线人.
- 干预:在住院期间教育和免费接种疫苗;常规护理:社区接种疫苗.
主要成果:
- 招募了518名高风患者.
- 干预组的疫苗覆盖率为89.9%,对照组为0.6%.
- 该策略达到了各种社会经济群体,并得到了患者和医疗保健专业人员的良好接受.
结论:
- 医院内流感疫苗接种策略是可行的,可接受的,以改善中国县级医院心力衰竭患者的VCR.
- 实施挑战包括报销,劳动力问责制和试验环境之外的能力.
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