肺癌手术后的慢性胸腔切除术后疼痛:对手术前风险因素的前性研究
Allan Vestergaard Danielsen1,2, Jan Jesper Andreasen1,2, Birthe Dinesen3
1Department of Cardiothoracic Surgery, Aalborg University Hospital, Aalborg, Denmark.
Scandinavian journal of pain
|June 16, 2023
概括
手术前的焦虑和抑郁,以及神经病痛症状,增加了患肺癌手术后慢性胸切除术后疼痛的风险. 早期识别可以指导预防策略.
科学领域:
- 疼痛医学 医学 疼痛医学
- 胸部外科手术 胸部外科手术
- 在瘤学瘤学.
背景情况:
- 慢性胸切除术后疼痛 (CPTP) 是肺癌手术后的一个重大问题.
- 手术前的心理因素和疼痛机制可能会影响CPTP的发展.
- 了解这些风险因素对于制定有效的疼痛管理策略至关重要.
研究的目的:
- 调查手术前疼痛机制,焦虑和抑郁以及患CPTP的风险之间的联系.
- 在接受肺癌手术的患者中确定CPTP的预测因素.
主要方法:
- 一项纵向队列研究,涉及121名接受视频辅助胸腔镜手术或肺癌前胸切除术的患者.
- 术前评估包括定量感官测试 (QST),神经病痛症状清单 (NPSI) 和医院焦虑和抑郁量表 (HADS).
- 在手术后六个月,CPTP使用数值评分表进行了评估.
主要成果:
- 46.3%的患者在六个月后报告了CPTP.
- 更高的手术前HADS得分 (p=0.025),NPSI得分 (p=0.009) 和急性术后疼痛 (p=0.042) 与CPTP的发展有关.
- 在手术前的QST评估或HADS子得分中没有发现显著差异.
结论:
- 术前焦虑,抑郁,神经病痛症状和急性术后疼痛与肺癌手术后的CPTP有关.
- 在手术前的QST评估中,预测CPTP没有显著差异.
- 在手术前确定高风险患者可以促进个性化的预防措施和疼痛管理.
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