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在患有玻璃眼瘤的患者中,PreserFlo MicroShunt 失败后开放式Bleb 修订的结果

Alicja Strzalkowska¹, Piotr Strzalkowski², Esther M Hoffmann¹

¹Department of Ophthalmology, Mainz University Medical Centre of the Johannes Gutenberg, University of Mainz, Mainz.

Journal of glaucoma

|June 16, 2023

概括

使用米托米辛-C的开放血栓修订有效降低 PreserFlo MicroShunt 血栓纤维化患者的眼内压 (IOP). 这种程序提供了一种安全有效的解决方案,用于管理植入后升高的IOP.

科学领域:

眼科医生眼科眼科
玻璃眼的手术玻璃眼的手术
眼睛表面手术眼睛表面手术

背景情况:

斑点纤维化是PreserFlo MicroShunt植入后的常见并发症,导致眼内压力升高 (IOP).
治理白内障纤维化对于保持青光眼排水装置的长期疗效至关重要.
开放式血栓修复与米托米辛-C (MMC) 是一个潜在的手术方法来解决这种并发症.

研究的目的:

评估使用MMC对在PreserFlo MicroShunt植入后的血栓纤维化开放血栓修订的有效性和安全性.
评估修订对眼内压力 (IOP) 的影响以及对青光眼药物的需要.

主要方法:

对27名接受MMC (0.2毫克/毫升3分钟) 开放血栓复查的患者进行了回顾性分析,以检测PreserFlo相关的血栓纤维化.
分析人口统计数据,青光眼的类型,手术前后的IOP,并发症和12个月内重复手术.

主要成果:

平均手术前内血压 26.4 ± 9.9 mm Hg 在第一周显著降低到 7.0 ± 2.7 mm Hg 和 15.9 ± 4.1 mm Hg 在12个月后修订.
四名患者在12个月需要IOP降压药物,四名患者需要第二次手术,以治疗复发性白血纤维化.
一名患者经历了积极的赛德尔测试,需要结膜.

结论:

使用MMC进行开放的血栓修复是一种有效和安全的程序,用于在PreserFlo植入后减少血栓纤维化患者的IOP.
外科手术的方法导致持续的IOP降低,在12个月后具有相似的药物负担.
这种修改技术提供了一个可行的选择,用于管理由于血栓痕而导致的失败的PreserFlo分流.

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