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Updated: Jul 26, 2025

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通过CRISPR/Cas9系统生成一个同卵性RANGRF淘汰的hiPSC线

Meiling Jiang1, Chengcheng Tang1, Xian Luo1

  • 1Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, South China Institute of Large Animal Models for Biomedicine, School of Biotechnology and Health Science, Wuyi University, Jiangmen, China.

Stem cell research
|June 16, 2023
PubMed
概括

研究人员创建了一个RAN关氨酸核酸释放因子 (RANGRF) 淘汰细胞系. 这种新型号有助于研究心肌病并测试治疗心脏病的基因疗法.

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相关概念视频

CRISPR/Cas9 Genome Editing01:28

CRISPR/Cas9 Genome Editing

The CRISPR-Cas system serves as a bacterial defense mechanism against invading genetic elements such as viruses and plasmids, forming the foundation for its adaptation as a powerful genome-editing tool. Originally discovered in prokaryotes, this system has been repurposed to revolutionize genetic engineering across a wide range of organisms, including plants, animals, and humans. The core component, Cas9, is an endonuclease derived from Streptococcus pyogenes, capable of introducing...
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