DELE1线.

Yusuke Sekine1, Ryan Houston2, Eva-Maria Eckl3

  • 1Aging Institute, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA; Division of Endocrinology and Metabolism, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Molecular cell
|June 16, 2023
PubMed
概括

缺铁会通过线粒体蛋白DELE1.1.激活血红受调的激酶HRI. 在线粒体上DELE1的稳定性触发了综合应激反应,保护细胞免受铁有限的死亡.

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