基于纤维素,pectin,carrageenan和alginate的口服药物递送系统的最新进展
Neera Raghav1, Chanchal Vashisth1, Nitika Mor1
1Chemistry Department, Kurukshetra University, Kurukshetra, Haryana 136119, India.
International journal of biological macromolecules
|June 16, 2023
概括
天然聚合物如纤维素,pectin,carrageenan和alginate对于口服药物输送系统非常适合. 本综述总结了其用于提高药物的生物可用性和疗效的最新进展.
科学领域:
- 制药科学 制药科学
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
背景情况:
- 聚合物对于药物输送系统至关重要,其性能优化了可溶性,释放性,向性,吸收性和有效性.
- 虽然有合成聚合物可供使用,但由于可访问性,可用性和安全性,天然聚合物被首选用于口服药物输送.
研究的目的:
- 审查最近 (过去五年) 关于使用四种关键天然聚合物的口服药物输送系统的文献:纤维素,pectin, carrageenan 和 alginate.
- 简要地呈现这些信息,并以表格格式呈现,以便读者轻松访问.
主要方法:
- 在科学数据库中对过去五年内发表的研究进行文献搜索.
- 数据提取和分类,重点关注基于天然聚合物的口服药物输送配方.
- 关于与纤维素,pectin,carrageenan和alginate一起使用的活性药物成分和辅料的信息表格.
主要成果:
- 关于使用纤维素,pectin,carrageenan和alginate用于口服药物输送的各种配方的广泛数据已被编制.
- 该审查强调了这些天然聚合物的多功能性和有效性在制药应用中.
- 信息以易于访问的表格格式呈现,以便快速参考.
结论:
- 自然聚合物为开发先进的口服药物输送系统提供了一个安全,可访问和有效的平台.
- 纤维素,pectin, carrageenan 和 alginate 是提高药物的生物可用性和治疗结果的有希望的候选者.
- 本综述是制药行业研究人员和配方人员的宝贵资源.
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