预防与饮食暴露相关的肠道损伤的挑战和策略
Pilar Rodríguez-Viso1, Adrián Domene2, Alicia Sánchez2
1Instituto de Agroquímica y Tecnología de Alimentos (IATA-CSIC), Paterna, Spain; Laboratory of Host-Microbiota Interactions, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warsaw, Poland.
Toxicology
|June 16, 2023
概括
饮食中的 (Hg) 暴露会通过胃肠道影响人类健康. 这次审查考察了.
科学领域:
- 毒理学 毒理学 毒理学
- 胃肠病学 胃肠病学
- 营养科学 营养科学
背景情况:
- 对于大多数人来说,食物是暴露于 (Hg) 的主要来源.
- 胃肠道的吸收对于进入人体至关重要.
- 毒性对肠道的影响是最近研究的重点.
研究的目的:
- 批判性地审查了解对肠道上皮的有毒作用的近期进展.
- 修改饮食策略,以减少的生物可用性和调节肠道反应.
- 讨论限制和未来的研究方向,以减轻毒性.
主要方法:
- 关于最近科学进展的文献综述.
- 对对肠道影响的毒理数据的评估.
- 对饮食干预措施的分析,包括食品成分和益生菌.
主要成果:
- 最近的研究强调了对肠道上皮的显著毒性影响.
- 饮食策略,包括特定的食物成分和益生菌,显示出降低生物可用性的潜力.
- 对表皮和微生物群反应的调节是饮食干预的关键领域.
结论:
- 饮食中的暴露带来了显著的风险,胃肠道是作用的关键地点.
- 饮食策略提供了有希望的方法,通过减少吸收和影响肠道健康来减轻的毒性.
- 需要进一步的研究来克服目前的局限性,并开发有效的干预措施.
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