差异成分估计和基因组范围的预测甲生产在杂交牛肉牛的协会
Andrew D Lakamp1, Cashley M Ahlberg1, Kristi Allwardt2
1Department of Animals Sciences and Industry, Kansas State University, Manhattan, KS 66506, USA.
Journal of animal science
|June 16, 2023
概括
遗传选择可以减少反动物的肠道甲排放. 预测的甲生产特征和基因组数据可以有效地进行基因评估,以减少温室气体的产生.
科学领域:
- 动物科学动物科学
- 遗传学 是一个遗传学.
- 环境科学 环境科学
背景情况:
- 肠道甲是显著的温室气体,在反动物中造成能量损失.
- 甲生产存在遗传变异,通过选择性育种提供了减少的潜力.
- 直接测量甲具有挑战性,这使得间接指标和遗传评估具有价值.
研究的目的:
- 评估使用预测的甲生产特征用于杂交牛的遗传选择的可行性.
- 评估不同甲预测模型的一致性及其对遗传评估的影响.
- 为了确定与预测的甲生产相关的遗传标记.
主要方法:
- 使用Ellis等人计算了830头杂交牛的3个预测的甲生产特征. (2007年),米尔斯等人. (2003年) 和IPCC (2019年) 的模型.
- 评估预测的特征和估计的繁殖值之间的相关性.
- 进行了全基因组关联研究 (GWAS),以确定显著的单核酸多态 (SNP).
主要成果:
- 所有三种甲预测方程都显示了彼此的高相关性 (>0.99),表明了相似的性能.
- 预测甲产生的遗传概率估计高 (0.59-0.62),支持遗传选择.
- 鉴定了与氧化还原酶活性相关的染色体7上显著的SNP,以及与原,微管和DNA转录相关的暗示性SNP.
结论:
- 预测的甲生产特征是反动物遗传选择的可靠指标.
- 包括SNP在内的基因组数据可以增强减少肠道甲排放的遗传进展.
- 参与氧化还原酶活性,原体,微管和DNA转录的基因可能会影响甲的产生.
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