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Updated: Jul 26, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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通过蛋白质语言模型改进了异构体蛋白质复合物的预测

Bo Chen1, Ziwei Xie2, Jiezhong Qiu3

  • 1Department of Computer Science and Technology, Tsinghua University, Beijing, China.

Briefings in bioinformatics
|June 16, 2023
PubMed
概括

使用蛋白质语言模型的新方法ESMPair识别了更好地相互作用的蛋白质同类物 (介质物) 以进行复杂结构预测. 这对AlphaFold-Multimer进行了改进,特别是在低置信度预测和真核生物复合体方面.

关键词:
阿尔法折叠多元器件蛋白质复杂结构预测 蛋白质复杂结构预测蛋白质语言模型

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