改善对高风险患者肝细胞癌监测的干预措施:一个范围审查
Eliza W Beal1, Molly McNamara2, Mackenzie Owen2
1Departments of Surgery and Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, 4100 John R, Mailcode: HW04HO, Detroit, MI, 48201, USA. ewbeal@gmail.com.
随着干预措施的实施,肝细胞癌 (HCC) 监测率有所改善,但遵从性仍然低于最佳水平. 需要进行进一步的研究,以确定在高风险患者中增加HCC监测的最有效策略.
科学领域:
- 肝病学和胃肠病学 肝病学和胃肠学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 肝细胞癌 (HCC) 是慢性肝病和慢性乙型肝炎感染的常见并发症.
- 国际指导方针建议对高风险个体进行两年一度的HCC监测.
- 目前的HCC监测率不足于最佳水平,在11%至64%之间.
研究的目的:
- 系统地审查和描述旨在改善HCC监测率的干预措施.
- 鉴定肝硬化或慢性肝病患者HCC监测的评估干预措施.
主要方法:
- 进行了系统的范围审查.
- 在PubMed和Embase数据库中对1990年1月至2021年9月期间发表的英语研究进行了搜索.
- 研究检查了旨在提高HCC监测率的干预措施.
主要成果:
- 包括14项研究,包括随机临床试验,准实验研究,前性和后性队列研究.
- 干预措施各不相同,包括邮寄邀请函,患者和提供者教育,患者导航,自动提醒和基于网络的工具.
- 所有审查的干预措施都表明,在实施后,HCC监测率有所增加.
结论:
- 虽然干预措施可以提高HCC监测率,但整体遵守情况仍然不够理想.
- 需要进一步分析,以确定哪些干预措施在增加HCC监测方面最有效.
- 开发多方策略和改进实施方法是必要的,以加强HCC监测的遵守.
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