文化适应的心理社会干预 (CaPSI) 对于低资源环境中的早期精神病:大型多中心RCT的研究方案
M O Husain1,2, A B Khoso3, T Kiran3
1Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, 1025 Queen St West, Toronto, ON, Canada. Omair.husain@camh.ca.
BMC psychiatry
|June 16, 2023
概括
这项研究测试了文化适应的认知行为疗法 (CaCBT) 和家庭干预 (CulFI) 针对巴基斯坦的第一发精神病 (FEP). 在低资源环境中,CaCBT和CulFI有望改善患者和护理人员的治疗结果.
科学领域:
- 精神病学是一个精神病学.
- 全球健康 全球健康
- 心理社会干预 心理社会干预
背景情况:
- 精神病治疗指南通常依赖于高收入国家的证据.
- 在低收入和中等收入国家 (LMICs) 早期精神病的比较心理社会干预方面存在有限的研究.
- 文化适应的干预措施对于经历第一次精神病发作 (FEP) 的不同人群至关重要.
研究的目的:
- 评估文化适应的认知行为疗法 (CaCBT) 和文化适应的家庭干预 (CulFI) 在巴基斯坦的临床疗效.
- 评估CaCBT和CulFI的成本效益与FEP的通常治疗 (TAU) 相比.
- 改善患者和护理人员在低资源环境中的结果.
主要方法:
- 一个多中心,三臂随机受控试验 (RCT) 涉及390名FEP患者.
- 这些干预措施包括CaCBT,CulFI和TAU.
- 主要结局是FEP整体症状的减少;次要结局包括患者和护理人员的福祉和功能.
主要成果:
- 关于主要结果的数据尚未提供,因为这是试验注册摘要.
- 这项研究旨在比较CaCBT和CulFI对TAU的疗效.
- 将分析经济影响和详细的患者/护理人员结果.
结论:
- 成功实施将有助于扩大对巴基斯坦和其他LMICs的干预.
- 文化上适应的心理社会干预措施可能会改善不同人群中FEP的结果.
- 这项研究解决了在缺乏资源的地区治疗精神病的证据的关键差距.
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