新血管性AMD的白内障手术:对视力敏度和疾病活动的影响
Hin Yan Tang1, Mats Rosén1, Elisabet Granstam2,3
1Department of Ophthalmology, County Hospital of Västmanland, Västerås, Sweden.
BMC ophthalmology
|June 16, 2023
概括
白内障手术改善了视力,并且没有改变新血管与年龄相关的黄斑变性 (nAMD) 的抗血管内皮生长因子 (VEGF) 治疗强度. 黄斑形态稳定,视内液的轻微增加没有影响结果.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 外科手术的结果
背景情况:
- 白内障和新血管与年龄相关的黄斑变性 (nAMD) 经常共存,影响视力.
- 白内障手术对nAMD活动的影响受到争论.
- 这项研究检查了白内障手术对视力敏度,nAMD治疗和黄斑形态的影响.
研究的目的:
- 调查白内障手术对视力敏度的影响.
- 为了评估抗血管内皮生长因子 (VEGF) 治疗强度的变化,对于手术后的nAMD.
- 在患有nAMD的患者中,评估白内障手术后黄斑形态的变化.
主要方法:
- 使用瑞典国家登记册和光学连贯性断层扫描 (OCT) 数据进行的回顾性研究.
- 包括156名接受白内障手术的患者 (168只眼睛),同时接受nAMD治疗.
- 手术后6个月进行了随访.
主要成果:
- 视力敏度明显改善了白内障手术后 (距离ETDRS字母增加).
- 抗VEGF治疗强度保持稳定.
- 观察到视网膜内液体的轻微增加,但黄斑形态 (视网膜下液体,视网膜中心厚度) 没有改变.
结论:
- 白内障手术可以提高nAMD患者的视力敏度,而不会增加nAMD活性或抗VEGF治疗需求.
- 观察到的内液增加可能是退行性的,并不会对视觉结果产生负面影响.
- 白内障手术对于患有同时存在的nAMD的患者来说是安全和有益的.
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