Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Fast Reactions01:27

Fast Reactions

Fast reactions occurring in times shorter than the time needed to mix reactants pose a unique challenge for investigation. In a liquid-phase continuous-flow system, reactants A and B are swiftly pushed into the mixing chamber, where mixing occurs within 1 ms. The reaction mixture then flows through an observation tube, and one measures light absorption to determine species concentrations at various points of the tube. This method is most appropriate when relatively large volumes of reactants...
Sampling Continuous Time Signal01:11

Sampling Continuous Time Signal

In signal processing, a continuous-time signal can be sampled using an impulse-train sampling technique, followed by the zero-order hold method. Impulse-train sampling involves the use of a periodic impulse train, which consists of a series of delta functions spaced at regular intervals determined by the sampling period. When a continuous-time signal is multiplied by this impulse train, it generates impulses with amplitudes corresponding to the signal's values at the sampling points.
In the...
Feedback control systems01:26

Feedback control systems

Feedback control systems are categorized in various ways based on their design, analysis, and signal types.
Linear feedback systems are theoretical models that simplify analysis and design. These systems operate under the principle that their output is directly proportional to their input within certain ranges. For instance, an amplifier in a control system behaves linearly as long as the input signal remains within a specific range. However, most physical systems exhibit inherent nonlinearity...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Clocked stepping of an artificial protein walker along a DNA track.

Nature nanotechnology·2026
Same author

Experiences Using Long-Term Consumer-Based Activity Tracking in Full-Scale RCTs.

Studies in health technology and informatics·2026
Same author

Trends in anxiety and depressive symptoms among adults in Norway based on eight population-based surveys from 1995 to 2024.

Discover mental health·2026
Same author

SmartTrap: automated precision experiments with optical tweezers.

Nature methods·2026
Same author

Life-course social and economic inequalities in non-communicable disease prevalence: the Tromsø Study (2015-2016).

Scandinavian journal of public health·2026
Same author

Serum per- and polyfluoroalkyl substances (PFAS) and bone mineral density in Norwegian adolescents: sex-specific associations and mixture effects.

Environment international·2026

相关实验视频

Updated: Jul 9, 2026

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
00:10

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

Published on: September 5, 2019

8.3K

在单分子实验中,信息转化为工作:从离散到连续的反.

Regina K Schmitt1, Patrick P Potts1, Heiner Linke1

  • 1Department of Physics and NanoLund, Lund University, Box 188, SE-221 00 Lund, Sweden.

Physical review. E
|June 17, 2023
PubMed
概括

我们在反的单分子实验中探索了可提取的工作. 我们的发现为了解工作提取效率和最大功率的最佳参数提供了一个框架,通过DNA发针模拟验证.

更多相关视频

An In Vitro Single-Molecule Imaging Assay for the Analysis of Cap-Dependent Translation Kinetics
09:52

An In Vitro Single-Molecule Imaging Assay for the Analysis of Cap-Dependent Translation Kinetics

Published on: September 15, 2020

3.2K
Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes
08:26

Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes

Published on: November 23, 2021

2.6K

相关实验视频

Last Updated: Jul 9, 2026

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules
00:10

Single-Molecule Tracking Microscopy - A Tool for Determining the Diffusive States of Cytosolic Molecules

Published on: September 5, 2019

8.3K
An In Vitro Single-Molecule Imaging Assay for the Analysis of Cap-Dependent Translation Kinetics
09:52

An In Vitro Single-Molecule Imaging Assay for the Analysis of Cap-Dependent Translation Kinetics

Published on: September 15, 2020

3.2K
Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes
08:26

Automated Two-dimensional Spatiotemporal Analysis of Mobile Single-molecule FRET Probes

Published on: November 23, 2021

2.6K

科学领域:

  • 热力学是一种热力学.
  • 单分子生物物理学的单分子生物物理.
  • 统计力学就是统计力学.

背景情况:

  • 单分子实验允许在纳米级探测基本的热力学过程.
  • 反控制对于操纵和从分子系统中提取工作至关重要.
  • 在反下理解工作提取是设计高效分子机器的关键.

研究的目的:

  • 在单分子展开折叠实验中理论上研究可提取的工作,并使用应用反.
  • 开发一个详细的波动定理,对获得的信息进行核算.
  • 为了确定最大功率或工作提取速度的参数.

主要方法:

  • 利用一个简单的两种状态模型来描述在离散和连续反下的工作分布.
  • 为平均工作提取及其实验可测量的边界衍生了分析表达式.
  • 员工波动定理用于量化反和信息获取的影响.

主要成果:

  • 通过不同的反制度 (离散到连续) 获得工作分配的完整描述.
  • 导出了用于平均工作提取和在连续反极限中严格限制的实验的分析表达式.
  • 确定了最大化功率或工作提取速度的参数.

结论:

  • 该研究为理解反控制单分子实验中的工作提取提供了理论框架.
  • 衍生的波动定理提供了关于信息在热力学过程中的作用的见解.
  • 研究结果显示,与DNA发针动态模拟的定性一致,这表明应用范围更广.