迟到但不早发作会对早期中风后恢复产生负面影响:一项病例对照研究
Bakary Samake1, Marion Houot2,3,4, Chiara Zavanone1
1Rehabilitation Unit, AP-HP, Pitié-Salpêtrière Hospital, Paris, France.
European stroke journal
|June 17, 2023
概括
卒中后的晚期发作会对功能恢复产生负面影响,并增加康复时间. 然而,早期发作不会显著影响康复结果,这表明基于时间的差异性影响.
科学领域:
- 神经学 神经学
- 脑卒中康复治疗 脑卒中康复治疗
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 发作是中风后的一个常见并发症.
- 最初的中风严重程度与发作发生和功能恢复较差有关.
研究的目的:
- 调查是否会对中风后功能恢复产生负面影响.
- 为了确定发作是否是一个独立的因素,还是仅仅是中风严重程度的代理因素.
主要方法:
- 对408名中风患者进行了回顾性病例对照研究.
- 根据中风类型,治疗,位置,程度,侧面和年龄,有和没有发作的患者的1:1匹配.
- 通过修改的兰金分数和停留时间来评估神经恢复,将发作分为早期 (≤7天) 或晚期 (>7天).
主要成果:
- 分析了110对匹配的中风患者,有和没有发作.
- 晚期发作与功能恢复较差 (Rankin评分) 和住院时间较长 (p<0.05) 相关.
- 早期发作对功能恢复指标没有显著影响.
结论:
- 晚期发作 (中风相关) 不利于早期的神经康复.
- 早期的症状性发作似乎不会对功能恢复产生负面影响.
- 这些发现支持目前的建议,反对治疗中风后的早期发作.
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