未来无关医疗成本的特定环境估计及其对成本效益分析的影响
Noga Epstein1, Tzahit Simon-Tuval2, Yakir Berchenko1
1Department of Industrial Engineering and Management, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
PharmacoEconomics
|June 17, 2023
概括
估计乳腺癌患者未相关的未来医疗费用 (UFMC) 对成本效益分析 (CEA) 的影响很小. 对UFMC假设的透明报告对于医疗保健中可靠的经济评估至关重要.
科学领域:
- 卫生经济学 卫生经济学
- 在瘤学瘤学.
- 医疗决策的制定 医疗决策的制定
背景情况:
- 成本效益分析 (CEA) 对医疗保健资源分配至关重要.
- 准确估计所有医疗保健费用,包括不相关的未来医疗费用 (UFMC),对于强大的CEA至关重要.
- 将UFMC纳入乳腺癌治疗CEA的影响仍然是一个需要进一步研究的领域.
研究的目的:
- 开发和应用估计乳腺癌妇女UFMC的方法.
- 评估包括UFMC在乳腺癌治疗CEA结果上的影响.
- 为了评估基于trastuzumab的化疗方案的成本效益.
主要方法:
- 使用14年的患者索赔数据进行回顾性队列研究.
- 使用对照对象的平均医疗费用和通用线性模型 (GLM) 的UFMC估计.
- 马尔科夫模拟模型用于CEA,比较使用/不使用trastuzumab,使用或不使用UFMC的化疗方案.
主要成果:
- 包括UFMC对增量成本效益比率 (ICER) 有了适度的影响.
- 与37000美元/QALY的支付意愿门相比,不管UFMC是否包括在内,Trastuzumab的成本效益并没有被发现.
- UFMC估计方法没有改变关于评估治疗的成本效益的总体结论.
结论:
- 将UFMC纳入此乳腺癌成本效益分析并没有显著改变该研究的结论.
- 当预计会对ICER产生重大影响时,应估计特定环境的UFMC.
- 在UFMC估计中使用假设的透明报告对于经济评估的完整性至关重要.
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